Bingmei Fu

Education

Postdoc, Department of Human Physiology, School of Medicine, University of California, Davis, 1995-1998
Ph.D. Mechanical Engineering, The City University of New York, 1995
M.S. Modern Mechanics, University of Science & Technology of China, 1988
B.S. Modern Mechanics, University of Science & Technology of China, 1985

Prefessional Experience

Associate Professor, 2004-present
Department of Biomedical Engineering
The City College of the City University of New York

Assistant-Associate Professor, 1998-2004
Department of Mechanical Engineering
Howard R. Hughes College of Engineering
University of Nevada, Las Vegas

Assistant Professor, 1988-1989
Department of Engineering Mechanics
Southwest Jiao Tong University, China

Awards & Honors

2002-2003 Distinguished Research Award
Howard R. Hughes College of Engineering, University of Nevada, Las Vegas
2002-2007 Career Award, NSF
1996-1998 Postdoctoral Fellowship
NIH Training Grant in Cardiology and Neurophysiology
1996 Harold Shames Biomedical Engineering Award for Graduate Excellence in Research
Center for Biomedical Engineering Consortium, City College of New York
1995 Whitaker Graduate Student Award for Best Paper
Biomedical Engineering Society

Research Interests

Molecular, Cell and Tissue Engineering in the Microcirculation

Modeling nano-micro transport phenomena in transvascular, transcelluar and transinterstitial processes
Structural mechanisms of acute increase of microvessel permeability
Tumor migration and metastasis in vivo
In vivo permeability studies on single microvessel
(microperfusion, quantitative video microscopy, fluorescence microscope photometry and confocal microscopy, image processing)
Regulation of vessel permeability by mechanical, physical and chemical stimuli
(signal transduction, permeability studies under physiological and pathological conditions)
Drug delivery to brain through the Blood-Brain Barrier and the CSF

Optimization in therapeudic medical device

Fluid Mechanics, Mass and Heat Transfer

Recent & Frequently Cited Publications

Chen, B. and Fu, B.M. A time-dependent electrodiffusion-convection model for charged macromolecule transport across the microvessel wall and in the interstitial space. Cellular and Molecular Bioengineering, in press, 2009.[PDF].
Lv, Y., Cheung, NK. V., and Fu, B.M.A Pharmacokinetic model for radioimmunotherapy delivered through cerebrospinal fluid for the treatment of leptomeningeal metastases. J. of Nuclear Medicine. 50(8): 1324-1331, 2009.[PDF].
Yuan, W. Lv, Y. Zeng, M. and Fu, B.M. Non-invasive measurement of solute permeability in cerebral microvessels of the rat. Microvas. Res., 77:166-173, 2009[PDF].
Chen, X.Y., Liu, Y. Fu, B.M., Fan, J.T., and Yang, J.M. MD simulation of colloidal particle transportation in a fiber matrix. Mol. and Cel. Biomechanics. 5(4):275-284, 2008.[PDF].
Liu, Q. Mirc D. and Fu, B.M. Mechanical mechanisms of thrombosis in intact bent microvessels of rat mesentery. J. of Biomechanics. 41: 2726-2734, 2008.[PDF].
Fu, B. M., Shen, S. and Chen, B. Structural Mechanisms in the Abolishment of VEGF-induced Microvascular Hyperpermeability by cAMP. ASME J. Biomech. Eng., 128(3):313-328, 2006.[PDF].
Sugihara-Seki, and Fu, B. M. Blood Flow and Permeability in Microvessels, Fluid Dynamics Research, 37:82-132, 2005.[PDF].
Ma, J., Guo, P., Zhang, J. Li, N. and Fu, B.M. Enhancement of Oxygen Transfer in Liquid Lead and Lead-bismuth Eutectic by Natural Convection. Int. J. of Heat and Mass Transfer, 48:2601-2612, 2005.[PDF].
Chen, B., Yee, T., Kiser, M. A. and Fu, B.M. A Multidimensional Optimization Process for Enhancing Electroacupuncture Efficiency. Medical Acupuncture, Vo. 16 (2):12-19, 2005.[PDF].
Fu, B. M., Adamson, R.H. and Curry, F.E. Determination of Microvessel Permeability and Tissue Diffusion Coefficient by Laser Scanning Confocal Microscopy. ASME J. Biomech. Eng. 127(2):270-278, 2005.[PDF].
Chen, B. and Fu, B. M. An Electrodiffusion-Filtration Model for Effects of Surface Glycocalyx on Microvessel Permeability to Macromolecules. ASME J. Biomech. Eng., 126:614-624, 2004.[PDF].
Yan, H., Jiang, Y. T., Zheng, J., Fu, B. M, Shao, S., Peng, C. The internet-based knowledge acquisition and management method to construct large-scale distributed medical expert systems. Comp. Methods and Programs in Biomedicine, 74, 1-10, 2004 [PDF].
Fu, B. M. and Shen, S. Acute VEGF effect on solute permeability of mammalian microvessels in vivo. Microvasc Res., 68(1):51-62, 2004 [PDF].
Fu, B.M. , and Chen, B. A Model for the Modulation of Microvessel Permeability by Junction Strands. ASME J. Biomech. Eng., Vol 125, 620-627, 2003 [PDF].
Guo, P., Hillyard, S.D., and Fu, B. M. A Two-Barrier Compartment Model for Volume Flow across Amphibian Skin. Am. J. of Physiol., 285, R1384-1394, 2003 [PDF].
Fu, B. M. and Shen, S. Structural mechanisms of vascular endothelial growth factor (VEGF) on microvessel permeability. Am J Physiol; 284(6): H2124-2135, 2003 [PDF].
Fu, B.M., Chen, B, and Chen, W. An Electrodiffusion Model for Effects of Surface Glycocalyx Layer on Microvessel Solute Permeability. Am. J. Physiol. 284: H1240-1250, 2003 [PDF].

Courses Taught

at UNLV

EGG 102/102L Introduction to Engineering Design (undergraduate)
CEG 303/303L Fluid Mechanics (undergraduate)
MEG 314 Heat transfer (undergraduate)
MEG 380/380L Fluid dynamics (undergraduate)
MEG 445/645 Numerical Methods for Engineers (undergraduate/graduate)
MEG 416/616 Introduction to Biomedical Engineering
(undergraduate/graduate)
MEG 700 Advanced Fluid Mechanics (graduate)
MEG 795 Transport Phenomena in Biology (graduate)

at CCNY

BME 50100 Cell and Tissue Mechanics (undergraduate)
BME 50200 Cell and Tissue Transport (undergraduate)
BME 50400 Cell and Tissue Engineering (undergraduate)
BME I2000 Cell and Tissue Engineering (graduate)
BME I2200 Cell and Tissue Transport (graduate)
BME I4200 Organ Transport and Pharmacokinetics (graduate)
BME I55100/G4300 Scientific Ethics (graduate/undergraduate)

Bingmei Fu
Associate Professor of Biomedical Engineering The City College of The City University of New York
Steinman Hall, T-435
212.650.7531
212.650.672
fu@ccny.cuny.edu
Fu Lab [..]